These tweets are selected automatically with #rstats code. Please inform me if any is inappropriate. See other #IHCPath pages here: https://serdarbalci.netlify.com/categories/IHCPath/ or here: https://serdarbalci.wordpress.com/?s=IHCPath/ See selected social media based textbook project here: http://www.patolojinotlari.com/
@Gleason4plus5 @wolfe_dr they are calling these tubulocystic RCC with "dedifferentiation" to high grade collecting duct CA #gupath
— Samson W. Fine, MD (@rovingatuscap) March 25, 2015
IgA nephropathy. Kidney, needle biopsy. PAS, PAM and IgA (DIF). pic.twitter.com/fUS7FIv3XY
— Pathology Walker@Auto Tweet Bot (@Patholwalker) January 6, 2019
Solitary fibrous tumor. Nasal cavity, tumorectomy. HE, stat6, Bcl-2 and CD34. pic.twitter.com/EIMeWe6pze
— Pathology Walker@Auto Tweet Bot (@Patholwalker) January 5, 2019
Distribution of proton pump(IHC). These show the difference between normal and atrophic mucosa. Stomach, gastrectomy. pic.twitter.com/rDlzkHME66
— Pathology Walker@Auto Tweet Bot (@Patholwalker) January 3, 2019
Nuclear atypia seen in angiomatous meningioma (common finding in AM) , WHO grade I. Cerebrum, resection. HE and EMA. pic.twitter.com/ce81QUM6GT
— Pathology Walker@Auto Tweet Bot (@Patholwalker) January 2, 2019
Tubular adenocarcinoma of stomach, HER2-enriched type. Stomach, biopsy. HE and HER2. pic.twitter.com/pBNg0lWPy8
— Pathology Walker@Auto Tweet Bot (@Patholwalker) January 1, 2019
Meningothelial meningioma, WHO grade I. HE and EMA. pic.twitter.com/EeP9Oc8Fdc
— Pathology Walker@Auto Tweet Bot (@Patholwalker) November 30, 2017
This is metastatic PTC to kidney. Noted the colloid. DDX: Thyroid-like follicular carcinoma of the kidney (TLFCK). PAX8 positive in both, need TTF-1/TG for ddx. Pic: TTF-1 pic.twitter.com/3eZ7tIoyeF
— Bin Xu (@BinXu16) January 3, 2020
this region of ch 12 has STAT6-GLI1-DDIT3-CDK4-HMGA2-MDM2. for GLI1-amplified tumor, it often has coamplification of adjacent genes, and sometimes immunopositivity of STAT6, CDK4, and MDM2.
— Bin Xu (@BinXu16) December 24, 2019
For Gli1-fusion tumor, one would need break apart probe and will not have coamplification
Epithelioid sarcoma vs. granuloma. INI1 results?
— Bin Xu (@BinXu16) December 20, 2019
+1 I would also do NE markers (last picture worrisome for HGNEC) and HPV. It is an interesting staining pattern. Sometimes you can also get carcinoma extending into ducts and the CK/p40 can be the basal/myoepithelial layer of duct (low power lobulated view+myoepi markers help).
— Bin Xu (@BinXu16) December 20, 2019
FS trick: unsure parathyroid vs. thyroid->polarize it: colloid has calcium oxylate crystals. #Endopath #Thyroid #pathology @DrGeeONE @KayKoMD @D4L14H @ariella8 @kriyer68 pic.twitter.com/nC6ILwUdR0
— Bin Xu (@BinXu16) December 20, 2019
Do you have ALK and MDM2 IHC? If positive, would help.
— Bin Xu (@BinXu16) November 22, 2018
also maybe do a CD34 and SMA
No sure. A few pics looks cardiac myxoma..but a few pic get too much cytological atypia..maybe need a work up for intimal sarcoma (MDM2) as well as some lymphoma. Cardiac IMT is also reported, but mostly affect young people....
— Bin Xu (@BinXu16) November 22, 2018
CCC to me by morphology and IHC.
— Bin Xu (@BinXu16) November 21, 2018
Myoepithelial ca should have at least some myoepithelial marker positivity (S100, SOX10, SMA, calponin, GFAP)
Basaloid scc to me too...do a p16 if it involve oropharynx, and safer to do synapt and chrom to ro small cell
— Bin Xu (@BinXu16) November 21, 2018
Lipid storage myopathy in an older child presenting with skeletal muscle weakness, myalgia and with markedly elevated serum creatine kinase level. He is under further investigation for DD. H&E, NADH-TR, Modified Trichrome, ORO stains #PediPath @SocPediPath @PaedPathSoc pic.twitter.com/ba0iXBW4uS
— ERDENER OZER (@ERDENEROZER) May 9, 2020
Different Clinical clusters would represent different processes at play. IL1 comes upstream of IL6 and is a sign of inflammasome activation. We need to concentrate on upstream pathways driving pathology. Renin>Angiotensin II>Angiotensin IV > tPAI-1 system needs attention.
— Dr Able Lawrence MBBS MD DM (@abledoc) May 9, 2020
Greg looks appropriately terrified.
— Paul Macklin (@MathCancer) May 2, 2020
(You would be too if you were being hunted by Red Skull.)
Mon AM Poster #138: Paari Murugan et al (GU-MSKCC) Type 1 papillary RCC: http://t.co/ueWPOhWM7N
— Samson W. Fine, MD (@rovingatuscap) March 4, 2014
(And the belly-laughing to yourself. Red flag for psych pathology and just really weird to boot.)
— Joshua Lander (@lander) February 1, 2020
These tweets are selected automatically with #rstats code. Please inform me if any is inappropriate. See other #IHCPath pages here: https://serdarbalci.netlify.com/categories/IHCPath/ or here: https://serdarbalci.wordpress.com/?s=IHCPath/ See selected social media based textbook project here: http://www.patolojinotlari.com/
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